Highway - Interstate 40

More of Interstate 40 passes through Tennessee, 455 miles (732 km), than any other state. The interstate goes through all of the three Grand Divisions of Tennessee and its three largest cities, Memphis, Nashville and Knoxville. Jackson, Lebanon, Cookeville, Crossville, and Newport are other notable cities and/or towns through which I-40 passes. Before leaving the state, I-40 enters the Great Smoky Mountains.